Unlock Your Mind's Potential

Personalized mental health care for depression, anxiety, and PTSD

Are you struggling to feel like yourself? Isha Health combines ketamine-assisted therapy with holistic care — available via telemedicine in 9 states.

Am I a Candidate?

Real Results from Real Patients

88.8%

of patients with moderate-to-severe depression show measurable improvement

92.6%

of anxiety patients reach minimal anxiety levels

Based on over 500 patients with validated PHQ-9 and GAD-7 assessments

See our full clinical outcomes report →
Meet our CEO Mai Shimada MD

Where Healing Meets Innovation

At Isha Health, we integrate the principles of neuroplasticity — the brain’s ability to reorganize and adapt — with a personalized treatment approach. This method has been pivotal in transforming our patients’ lives, with 88.8% showing measurable improvement.

Our approach doesn’t just treat symptoms — it fosters healing from within. Every person’s journey is unique, which is why careful personalization is at the core of everything we do.

*Based on PHQ-9 assessments across 546 patients. See full outcomes report →

Case Study

Joseph, Art Director

Despite a challenging upbringing, Joseph from Cambria, CA managed to forge successful careers in adolescent psychology and illustration. However, after years of unsatisfactory results from various antidepressants and psychotherapy, he turned to our clinic for his long-standing depression and anxiety.

“I was aware of my feelings. I found myself enjoying myself in a way I had never been able to.”

Joseph described his experience with ketamine-assisted therapy as not only pleasant but also educational. He was finally able to enjoy life in a way that had previously eluded him.

Watch Joseph’s Testimonial →

How It Works

From consultation to your first session — everything happens from home.

1

Meet Your Doctor

60-minute video consultation with a thorough assessment of your symptoms, medical history, and goals.

2

Receive Your Medication

Your prescription is sent to a compounding pharmacy. Medication arrives at your door within 3–5 business days.

3

Prepare with Your Team

You’ll receive thorough session instructions via email. Message the Isha team anytime with questions.

4

Your First Session

Place the ketamine tablet under your tongue and relax on your couch or bed with an eye mask. Effects last about 2 hours.

Get Started

Why Choose Isha Health

For depression and anxiety treatment that actually works.

Faster and Better Outcomes

Unlike conventional medications that take months, ketamine therapy can yield rapid responses. Many patients report improvement within weeks — some within days.

Affordable, Accessible Telehealth

Through telemedicine and sublingual ketamine, treatment is both cost-effective and convenient — all from your home. $350 per consultation, monitored by experienced clinicians.

Personalized, Evidence-Based

With over 50 years of safety data, ketamine is well-established. Your treatment plan is carefully supervised by clinicians with extensive ketamine therapy experience.

What Our Patients Say

Real stories from real patients across the country

Ketamine assisted therapy helped me so much to get out of my depression and PTSD. I never felt better in my life.

Amber S, Brooklyn, New York

My anxiety is just gone. I barely think about it anymore. It wasn’t instantaneous, but it worked eventually.

Patricia L, Santa Monica, California

I tried IV ketamine for my TRD before and it was too much for me. Isha’s approach is gentler on my body and worked great.

Laila L, New York, New York

Ketamine therapy is the only treatment that has worked for my depression and anxiety.

Rakesh V, Seattle, Washington

I have been able to come off from my meds for the past month. I am hopeful that I no longer need SSRIs in the future.

David S, Denver, Colorado

I felt that my anxiety and depression melting away even during the first session.

Cynthia L, Mountain View, California

I was recommended ECT for my severe depression. Then I found Isha. I am grateful.

Elliot M, San Francisco, California

You saved my life. My anxiety is under control, and I finally feel like myself again.

Emily P, Miami, Florida

I can’t thank Isha Health enough for helping me overcome my depression and anxiety. Ketamine therapy has truly been a game-changer.

Robert C, Beverly Hills, California

I started ketamine therapy for my depression. It ended up also helping me stop drinking. I’m sober for 6 months by now.

Sergey M, San Francisco, California

I was super nervous in the beginning but I quickly noticed my mood and motivation were improving after a week.

Marc I, Miami, Florida

Ketamine really worked for my anxiety. I don’t even remember when I last had a panic attack. I used to have it daily.

Jared Y, Rochester, New York

IV ketamine worked but I could not afford to continue. Isha really saved me.

Kurt Z, Brooklyn, New York

I just wanted to feel better. I actually now feel better.

Levi S, Escondido, California

I was able to come off from SSRIs through ketamine therapy. I feel that my depression is now more manageable.

Osi M, San Luis Obispo, California

These sessions have been transformative and have made me braver to embrace my interactions with others.

Kenneth M, Monterey, California

Thank you. I just want to say thank you to get me out of a pit of depression.

Rachel M, New York, New York

I’m so glad that I found Isha Health for my depression and anxiety. I love that I can speak and message with my doctor as many times as I’d like.

Annika W, Oakland, California

A Collaborative Approach to Care

Ketamine therapy works best when it’s part of a broader care plan. That’s why we work alongside therapists, psychologists, and counselors who specialize in ketamine-assisted psychotherapy.

Our physician prescribes and monitors your treatment, while your therapist provides the integration support that deepens and sustains your progress. This collaborative model is how we achieve an 88.8% improvement rate.

Mai Shimada, MD

Founder

Mai Shimada, MD

Double board-certified physician. Medical degree from The University of Tokyo, postdoctoral research at Harvard. Founded Isha Health to make evidence-based ketamine therapy accessible through telemedicine.

Jennifer S. Birch, NPJenya Kaufman, MDMargaret Brako, LCSWPerrin Elisha, PhDSandy Kong, LMFTKatie Chaudry, LCSWSusan Ono, PsyDVincent Rozalski, PhDJyoti Nadhani, LMFT

Our network includes 600+ clinicians across the country — psychiatrists, psychologists, LMFTs, and LCSWs.

Browse the Clinician Directory

In the News

Hundreds of thousands of patients are on their healing journey with ketamine therapy

Forbes The New Yorker Glamour

Learn More

Evidence-based insights on ketamine therapy from our clinical team

Clinical Data

Patient Outcomes & Clinical Results

88.8% improvement rate across 546 patients. PHQ-9, GAD-7, and retention data.

Patient Story

Julian's Story: When Ketamine Worked

A senior attorney with treatment-resistant depression found rapid relief.

Cost & Insurance

How Much Does Ketamine Therapy Cost?

Pricing, insurance options, and what to expect financially.

View all articles →

Stay informed on ketamine therapy

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