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Taking care of your mental health can be hard.
We made it easier.
Start your healing journey with our at-home ketamine therapy with personalized care plan

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Join thousands of people reclaiming their mental health

“Ketamine assisted therapy helped me so much to get out of my depression and PTSD.
I never felt better in my life."

Amber S from Brooklyn, New York

“I’m so glad that I found Isha Health for my depression and anxiety. I love that I can speak and message with my doctor as many times as I’d like without extra charges. I was very nervous in the beginning but she made me at ease through ketamine treatment."

Annika W from Oakland, California

“My anxiety is just gone. I barely think about it anymore. It wasn't instantaneous, but it worked eventually.

Patricia L from Santa Monica, California

“These sessions have been transformative and have made me braver to embrace my interactions with others not being overwhelmed with anxiety"

Kenneth M from Monterey, California

“I tried IV ketamine for my TRD before and it was too much for me. Isha's approach is gentler on my body and worked great."

Laila L from New York, New York

“Ketamine therapy is the only treatment that has worked for my depression and anxiety."

Rakesh V from Seattle, Washington

“I have been able to come off from my meds for the past month. I am hopeful that I no longer need SSRIs in the future."

David S from Denver, Colorado

“I felt that my anxiety and depression melting away even during the first session. Dr. Shimada and Angela made me feel at ease through out the treatment."

Cynthia L from Mountain View, California

“I had some ups and down in the beginning but after 3 weeks now I feel confident that ketamine therapy will continue to work for my depression."

Annette R from Santa Barbara, California

“I was recommended ECT for my severe depression. Then I found Isha. I am grateful."

Elliot M from San Francisco, California

“Isha doctor is very helpful, thorough, and really cares. Highly recommend."

LaKisha J from Venice Beach, California

“I am thankful to Isha Health for making ketamine treatment accessible. You are a life saviour."

Josephine M from Anaheim, California

"I can't thank Isha Health enough for helping me overcome my depression and anxiety. Ketamine therapy has truly been a game-changer."

Robert C from Beverly Hills, California

"You saved my life. My anxiety is under control, and I finally feel like myself again."

Emily P from Miami, Florida

"Ketamine treatment with Isha Health has given my life back. It was a gradual process, but I've never felt better."

James D from Bellevue, Washington

"Isha Health's approach to ketamine therapy has made all the difference for my mental health. I'm now more confident and less burdened by depression."

Sophia H from Boulder, Colorado

"After trying various treatments, ketamine therapy at Isha Health was the only thing that truly worked for my depression. It's been a life-changing experience."

Daniel M from Santa Clara, California

"I'm grateful to have found Isha Health. The doctor really cares. I wish I had found them much sooner."

Lily S from Hollywood, California

"Ketamine therapy at Isha Health has helped me regain control over my life. It’s a lot of self work and it’s worth it."

William L from Tampa, Florida

"Isha Health's doctors and staff have been exceptional. Ketamine therapy has given me hope for a brighter future without relying on SSRIs."

Sarah J from Spokane, Washington

"I was skeptical at first, but Isha's ketamine therapy has transformed my outlook on life. I'm so grateful for this treatment and the team's support."

Brian G from Denver, Colorado

"Ketamine therapy with Isha Health has been a lifeline for my depression. I finally feel like I have the tools to manage my depression."

Jennifer W from Palo Alto, California

"Dr.Mai’s commitment to making ketamine treatment accessible made a huge difference in my life. Thank you for providing a path to healing."

Alex K from Fort Lauderdale, Florida

"I’ve been in therapy for depression for years and adding ketamine treatment really accelerated my growth. I highly recommend their services."

Rachel S from Tacoma, Washington

“IV ketamine worked but I could not afford to continue. Isha really saved me.”

Kurt Z from Brooklyn, New York

“Thank you. I just want to say thank you to get me out of a pit of depression.”

Rachel M from New York, New York

“The experience was very different from what I expected. It made me reflect on many things without getting emotionally triggered. As I learned to face them rather than turn away from them, I think my anxiety subsided. "

Mia L from New York, New York

“I am thankful to Isha Health for making ketamine treatment accessible. You are a life saviour."

Josephine M from Anaheim, California

“I started ketamine therapy for my depression. It ended up also helping me stop drinking. I’m sober for 6 months by now”

Sergey M from San Francisco, California

“I just wanted to feel better. I actually now feel better.”

Levi S from Escondido, California

“I was super nervous in the beginning but I quickly noticed my mood and motivation were improving after a week. I realized that I identified myself with depression for a long time. I no longer think that way.”

Marc I form Miami, Florida

“I was able to come off from SSRIs through ketamine therapy. I feel that my depression is now more manageable. I am so grateful.”

Osi M from San Luis Obispo, California

“Ketamine really worked for my anxiety. I don't even remember when I last had a panic attack. I used to have it daily.”

Jared Y from Rochester, New York

“I tend to have the worst depression around this time of the year. There are ups and downs but I still feel generally good!”

Karen R from Phoenix, Arizona

Meet our CEO, Mai Shimada MD, sharing her story and vision behind Isha Health's online at-home ketamine clinic for depression and anxiety treatment



“Ketamine, an FDA-approved medication known for its biological and cognitive impacts, marks a pivotal milestone in the realm of healing. Our methodologies are strategically crafted to leverage ketamine's potential in enhancing neuroplasticity – the brain's innate capacity to heal and establish fresh connections.Following the treatment, *86% of Isha Health clients report improvements in symptoms of depression and anxiety.”

*Clients with moderate to severe symptoms.

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Joseph Murphy

Despite a challenging upbringing, Joseph Murphy from Cambria, CA managed to forge successful careers in adolescent psychology and illustration/art directing.However, after years of unsatisfactory results from various antidepressants and psychotherapy, he turned to our clinic in search of a solution for his long-standing depression and anxiety.

“I was aware of my feelings. I found myself enjoying myself in a way I had never been able to.”

Joseph described his experience with ketamine-assisted therapy as not only pleasant but also educational. He expressed how he was finally able to enjoy life in a way that had previously eluded him.

Watch Joseph's testimonial on the transformative effects of ketamine therapy.

Watch Joseph's Testimonial on Ketamine Therapy

Real patient testimonial for effective ketamine therapy - Isha Health
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How it works

1. Meet AN Isha Health Licensed Provider

Start your path by arranging a telehealth consultation, which will involve a thorough assessment. This helps us determine your suitability for ketamine therapy and allows us to design a personalized treatment strategy that matches your unique requirements.(If you aren’t a fit, you will not get charged for the visit.)

2. Receive Your Shipment

After your consultation, you will receive your medication delivered to your door.

3. Prepare for your session with Isha team

You will receive thorough instructions for your session. You can message Isha team as many times as you like if you have any questions. You also have access to a complimentary video call with our clinician to help you get ready for your first session.

4. Your First Session

Once your space is prepared, start the treatment by situating the ketamine tablet under your tongue. The effects of the medicine persist for approximately 1.5 hours, during which you'll unwind on a sofa or bed, adorned with an eye mask.

How it works
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1. Faster and better outcomes

In contrast to conventional medications and psychotherapy, which typically demand several months to exhibit symptom improvements, ketamine therapy yields rapid responses. Numerous patients attest to enhanced well-being within weeks, and in certain instances, even days.

2. Affordable and accessible telehealthcare 

Through the integration of telemedicine and sublingual ketamine treatment, healthcare becomes both cost-effective and within easy reach, all within the confines of your personal space. Our offerings encompass supervised ketamine treatment, overseen by proficient medical practitioners, at a rate of $350 per month.

3. A personalized, evidence-based approach

With a track record of over 50 years in healthcare, ketamine has been proven to be a safe treatment option. Your personalized treatment plan will be carefully supervised by clinicians who possess extensive experience in providing ketamine treatment. You can trust in their expertise to ensure your safety throughout the process.

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Expert and compassionate medical professionals for personalized ketamine therapy - Isha Health

Mai Shimada, MD
Founder & CEO

Jennifer Birch, PMHNP-BCPsychiatric Nurse Practitioner

Jennifer Birch, PMHNP-BC
Psychiatric Nurse Practitioner

Jenya Kaufman, MDBoard-certified Psychiatrist

Jenya Kaufman, MD
Board-certified Psychiatrist

Margaret Brako, LCSWLicensed Psychotherapist

Margaret Brako, LCSW
Licensed Psychotherapist

Vincent Rozalski, Ph.DLicensed Psychotherapist

Vincent Rozalski, Ph.D
Licensed Psychotherapist

Sarah Carr, LMFTLicensed Psychotherapist

Sarah Carr, LMFT
Licensed Psychotherapist

Sarah Murray, LMFTLicensed Psychotherapist

Sarah Murray, LMFT
Licensed Psychotherapist

Perrin Elisha, PhDClinical Psychologist

Perrin Elisha, PhD
Clinical Psychologist

Susan Ono, PsyDLicensed Psychotherapist

Susan Ono, PsyD
Licensed Psychotherapist


Hundres of thousands of patients are in their healing journey with ketamine therapy

The New Yorker
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