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Join thousands of people reclaiming their mental health

“Ketamine assisted therapy helped me so much to get out of my depression and PTSD.
I never felt better in my life."

Amber S from Brooklyn, New York

“I’m so glad that I found Isha Health for my depression and anxiety. I love that I can speak and message with my doctor as many times as I’d like without extra charges. I was very nervous in the beginning but she made me at ease through ketamine treatment."

Annika W from Oakland, California

“My anxiety is just gone. I barely think about it anymore. It wasn't instantaneous, but it worked eventually.

Patricia L from Santa Monica, California

“These sessions have been transformative and have made me braver to embrace my interactions with others not being overwhelmed with anxiety"

Kenneth M from Monterey, California

“I tried IV ketamine for my TRD before and it was too much for me. Isha's approach is gentler on my body and worked great."

Laila L from New York, New York

“Ketamine therapy is the only treatment that has worked for my depression and anxiety."

Rakesh V from Seattle, Washington

“I have been able to come off from my meds for the past month. I am hopeful that I no longer need SSRIs in the future."

David S from Denver, Colorado

“I felt that my anxiety and depression melting away even during the first session. Dr. Shimada and Angela made me feel at ease through out the treatment."

Cynthia L from Mountain View, California

“I had some ups and down in the beginning but after 3 weeks now I feel confident that ketamine therapy will continue to work for my depression."

Annette R from Santa Barbara, California

“I was recommended ECT for my severe depression. Then I found Isha. I am grateful."

Elliot M from San Francisco, California

“Isha doctor is very helpful, thorough, and really cares. Highly recommend."

LaKisha J from Venice Beach, California

“I am thankful to Isha Health for making ketamine treatment accessible. You are a life saviour."

Josephine M from Anaheim, California

"I can't thank Isha Health enough for helping me overcome my depression and anxiety. Ketamine therapy has truly been a game-changer."

Robert C from Beverly Hills, California

"You saved my life. My anxiety is under control, and I finally feel like myself again."

Emily P from Miami, Florida

"Ketamine treatment with Isha Health has given my life back. It was a gradual process, but I've never felt better."

James D from Bellevue, Washington

"Isha Health's approach to ketamine therapy has made all the difference for my mental health. I'm now more confident and less burdened by depression."

Sophia H from Boulder, Colorado

"After trying various treatments, ketamine therapy at Isha Health was the only thing that truly worked for my depression. It's been a life-changing experience."

Daniel M from Santa Clara, California

"I'm grateful to have found Isha Health. The doctor really cares. I wish I had found them much sooner."

Lily S from Hollywood, California

"Ketamine therapy at Isha Health has helped me regain control over my life. It’s a lot of self work and it’s worth it."

William L from Tampa, Florida

"Isha Health's doctors and staff have been exceptional. Ketamine therapy has given me hope for a brighter future without relying on SSRIs."

Sarah J from Spokane, Washington

"I was skeptical at first, but Isha's ketamine therapy has transformed my outlook on life. I'm so grateful for this treatment and the team's support."

Brian G from Denver, Colorado

"Ketamine therapy with Isha Health has been a lifeline for my depression. I finally feel like I have the tools to manage my depression."

Jennifer W from Palo Alto, California

"Dr.Mai’s commitment to making ketamine treatment accessible made a huge difference in my life. Thank you for providing a path to healing."

Alex K from Fort Lauderdale, Florida

"I’ve been in therapy for depression for years and adding ketamine treatment really accelerated my growth. I highly recommend their services."

Rachel S from Tacoma, Washington

“IV ketamine worked but I could not afford to continue. Isha really saved me.”

Kurt Z from Brooklyn, New York

“Thank you. I just want to say thank you to get me out of a pit of depression.”

Rachel M from New York, New York

“The experience was very different from what I expected. It made me reflect on many things without getting emotionally triggered. As I learned to face them rather than turn away from them, I think my anxiety subsided. "

Mia L from New York, New York

“I am thankful to Isha Health for making ketamine treatment accessible. You are a life saviour."

‍Josephine M from Portland, Oregon

“I started ketamine therapy for my depression. It ended up also helping me stop drinking. I’m sober for 6 months by now”

Sergey M from San Francisco, California

“I just wanted to feel better. I actually now feel better.”

Levi S from Escondido, California

“I was super nervous in the beginning but I quickly noticed my mood and motivation were improving after a week. I realized that I identified myself with depression for a long time. I no longer think that way.”

Marc I form Miami, Florida

“I was able to come off from SSRIs through ketamine therapy. I feel that my depression is now more manageable. I am so grateful.”

Osi M from San Luis Obispo, California

“Ketamine really worked for my anxiety. I don't even remember when I last had a panic attack. I used to have it daily.”

Jared Y from Rochester, New York

“I tend to have the worst depression around this time of the year. There are ups and downs but I still feel generally good!”

Karen R from Phoenix, Arizona

Meet our CEO, Mai Shimada MD, sharing her story and vision behind Isha Health's online at-home ketamine clinic for depression and anxiety treatment

Where Healing Meets Innovation: 86% Positive Response in Our Patients

Harnessing Neuroplasticity: The Power of Holistic Healing

At Isha Health, we are at the forefront of integrating the groundbreaking principles of neuroplasticity with our holistic treatment approach. Neuroplasticity, the brain’s remarkable ability to reorganize and adapt, is a cornerstone of our healing practices. This innovative method has been pivotal in transforming the lives of our patients, with an astounding *86% reporting positive outcomes. Our approach does not just treat the symptoms; it dives deeper, fostering healing from within and promoting long-term well-being. We believe in empowering our patients by activating their body’s intrinsic healing potential, leading to sustained health improvements. This unique blend of traditional wisdom and modern science exemplifies our commitment to delivering not just health care, but life care.

*Clients with moderate to severe symptoms.

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Joseph, Art director

Despite a challenging upbringing, Joseph from Cambria, CA managed to forge successful careers in adolescent psychology and illustration/art directing. However, after years of unsatisfactory results from various antidepressants and psychotherapy, he turned to our clinic in search of a solution for his long-standing depression and anxiety.

“I was aware of my feelings. I found myself enjoying myself in a way I had never been able to.”

Joseph described his experience with ketamine-assisted therapy as not only pleasant but also educational. He expressed how he was finally able to enjoy life in a way that had previously eluded him.

Watch Joseph's testimonial on the transformative effects of ketamine therapy.

Watch Joseph's Testimonial on Ketamine Therapy

Real patient testimonial for effective ketamine therapy - Isha Health
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How it works

1. Meet AN Isha Health DOCTOR

To begin your treatment, we start with a 60-minute video consultation that includes a thorough assessment. During this session, we will ask various questions about your current symptoms, medical history, and other relevant factors to comprehensively evaluate your condition. This helps us determine your suitability for our ketamine therapy and allows us to design a personalized treatment strategy that matches your unique requirements.

2. Receive Your Shipment

After your consultation, your prescription for oral ketamine will be sent to a compounding pharmacy. If you have a preferred pharmacy, we can send the prescription to the pharmacy as well. Once the prescription is processed, you can typically expect to receive your medication delivered to your door within 3-5 business days.

3. Prepare for your session with Isha team

You will receive thorough instructions for your session via email before your medication arrives. You can message the Isha team as many times as you like if you have any questions.

4. Your First Session

Once your space is prepared, start the treatment by placing the ketamine tablet under your tongue. The effects of the medicine persist for approximately 2 hours, during which you'll unwind on a sofa or bed, adorned with an eye mask.

How it works
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1. Faster and better outcomes

In contrast to conventional medications and psychotherapy, which typically demand several months to exhibit symptom improvements, ketamine therapy yields rapid responses. Numerous patients attest to enhanced well-being within weeks, and in certain instances, even days.

2. Affordable and accessible telehealthcare 

Through the integration of telemedicine and sublingual ketamine treatment, ketamine treatment becomes both cost-effective and within easy reach, all within the confines of your personal space. Our offerings include ketamine treatment, with progress monitored by proficient medical practitioners, at a rate of $350 per month.

3. A personalized, evidence-based approach

With a track record of over 50 years in healthcare, ketamine has been proven to be a safe treatment option. Your personalized treatment plan will be carefully supervised by clinicians who possess extensive experience in providing ketamine treatment. You can trust in their expertise to ensure your safety throughout the process.

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Clinical Team

Mai Shimada, MD

Founder & CEO

Dr. Mai Shimada is a board certified emergency medicine physician with over 10 years of experience. She decided to start Isha Health after discovering the transformative benefits of ketamine therapy for various mental health condition....(Read More)

Akua Brown, MD

Board Certified Physician

Dr. Akua Brown specializes in psychedelic medicine with a focus on increasing accessibility, education, and safety in the field. Fluent in both Spanish and English, she adopts community-focused approaches that mirror her identity as a Black American, queer, nature lover, and abolitionist...(Read More)

Jennifer S. Birch, NP

Psychiatric Nurse Practitioner

Berkeley, California

Jennifer, an experienced Psychiatric Nurse Practitioner from Yale University, specializes in treating mental health conditions like depression and anxiety. She focuses on empowering patients with clear treatment information.

Jenya Kaufman, MD

Board-certified Psychiatrist

San Francisco, California

Dr. Jenya Kaufman is a Stanford graduate and board-certified psychiatrist from UCSF. She has completed a comprehensive Psychedelic Facilitation Course at UC Berkeley, equipping her with a deep understanding of psychedelic integration practices.

Margaret Brako, LCSW


Berkeley, California

Margaret is passionate about helping people empower themselves. Her practice emphasizes trauma-informed and culturally responsive care for people of all backgrounds.

Sarah Carr, LMFT

San Francisco, California

Sarah Carr, LMFT is the Founder and Clinical Director of mindfulSF. Sarah has extensive training in Ketamine Assisted Psychotherapy (KAP) and has completed the Internal Family Systems (IFS) and Ketamine Assisted Psychotherapy Intensive through the Ketamine Training Center and IFS Institute.

Vincent Rozalski, Ph.D


San Francisco, California

Vincent specializes in focused treatment for individuals who are suffering from the after effects of trauma and other stressful events. He has worked with people who've experienced a variety of terrible events, such as combat, accidents, abuse, sexual assaults, and near death experiences.

Sarah Murray, LMFT


Denver, Colorado

Sarah is an experienced therapist dedicated to guiding individuals on a journey back to their authentic selves. Feeling detached, disconnected, or stuck? Sarah specializes in utilizing emotional, somatic, cognitive, and spiritual approaches to help you rediscover your innate strength and wisdom.

Perrin Elisha, PhD

Clinical Psychologist

Aspen, CO

Perrin Elisha, PhD, a clinical psychologist, specializes in psychosomatics and eating disorders. Author of "The Conscious Body" and founder of Relationships ReWired, she focuses on improving relationship health and intimate dynamics.

Sandy Kong, LMFT


San Jose, CA

Sandy Kong is a culturally sensitive therapist focused on providing a safe space for healing and growth. She uses her background and expertise to empower clients towards a balanced life.

Katie Chaudry, LCSW


Santa Monica, CA

Katie Chaudry offers a holistic approach to therapy, emphasizing judgment-free support for those navigating life's challenges. Specializing in anxiety, trauma, and personal growth, she draws from her own experiences to provide practical guidance and support to young adults seeking a more meaningful life.

Jyoti Nadhani, LMFT


Palo Alto, CA

Jyoti Nadhani, blending business acumen with counseling expertise, offers holistic, non-judgmental therapy focused on growth and healing. Her practice includes psychedelic-assisted therapy and is rooted in personal experiences with yoga and mindfulness, guiding clients towards a fulfilling life.


Hundres of thousands of patients are in their healing journey with ketamine therapy

The New Yorker
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